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Báo cáo y học: " Interrelated modulation of endothelial function in Behcet's disease by clinical activity and corticosteroid treatmen"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Interrelated modulation of endothelial function in Behcet's disease by clinical activity and corticosteroid treatment. | Available online http arthritis-research.eom content 9 5 R90 Open Access Research article Interrelated modulation of endothelial function in Behcet s disease by clinical activity and corticosteroid treatment Athanase D Protogerou1 Petros P Sfikakis2 Kimon S Stamatelopoulos1 Christos Papamichael1 Kostas Aznaouridis1 Emmanuil Karatzis1 Theodore G Papaioannou1 Ignatios Ikonomidis3 Phedon Kaklamanis2 Myron Mavrikakis1 and John Lekakis3 1Vascular Laboratory Department of Clinical Therapeutics Alexandra Hospital Medical School University of Athens V. Sofias 115 28 Athens Greece 21 st Department of Propeudeutic and Internal Medicine Laikon Hospital Medical School University of Athens Ag. Thoma 115 27 Athens Greece 32nd Department of Cardiology Attikon Hospital Medical School University of Athens Rimini 124 61 Athens Greece Corresponding author Athanase D Protogerou aprotog@med.uoa.gr Received 30 Apr 2007 Revisions requested 11 Jun 2007 Revisions received 18 Jul 2007 Accepted 11 Sep 2007 Published 11 Sep 2007 Arthritis Research Therapy 2007 9 R90 doi 10.1186 ar2289 This article is online at http arthritis-research.com content 9 5 R90 2007 Protogerou et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Corticosteroids are commonly used in empirical treatment of Behget s disease BD a systemic inflammatory condition associated with reversible endothelial dysfunction. In the present study we aimed to dissect the effects of clinical disease activity and chronic or short-term corticosteroid treatment on endothelial function in patients with BD. In a case-control crosssectional study we assessed endothelial function by endothelium dependent flow mediated dilatation FMD at the brachial artery of 87 patients who either were or .