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Báo cáo khoa học: " Chemotherapy followed by low dose radiotherapy in childhood Hodgkin's disease: retrospective analysis of results and prognostic factors"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Chemotherapy followed by low dose radiotherapy in childhood Hodgkin's disease: retrospective analysis of results and prognostic factors. | Radiation Oncology BioMed Central Open Access Chemotherapy followed by low dose radiotherapy in childhood Hodgkin s disease retrospective analysis of results and prognostic factors Gustavo A Viani 1 Marcus S Castilho1 Paulo E Novaes1 Celia G Antonelli2 Robson Ferrigno1 Cassio A Pellizzon1 Ricardo C Fogaroli1 Maria A Conte1 and Joao V Salvajoli1 Address Department of Radiation Oncology Hospital do Câncer SaoPaulo Brazil and 2Department of Pediatric Oncology Hospital do Câncer Sao Paulo Brazil Email Gustavo A Viani - gusviani@gmail.com Marcus S Castilho - marcscastilho@ig.com.br Paulo E Novaes - novaespe@uol.com.br Celia G Antonelli - gusviani@gmail.com Robson Ferrigno - rferrigno@uol.com.br Cassio A Pellizzon - cpellizzon@walla.com Ricardo C Fogaroli - rcfogaroli@ig.com.br Maria A Conte - contemaia@uol.com.br Joao V Salvajoli - jvsalvajoli@uol.com.br Corresponding author Published 02 October 2006 Received 04 May 2006 Radiation Oncology 2006 1 38 doi 10.1186 1748-717X-1-38 Accepted 02 October 2006 This article is available from http www.ro-journal.com content 1 1 38 2006 Viani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Purpose To report the treatment results and prognostic factors of childhood patients with Hodgkin s disease treated with chemotherapy CT followed by low dose radiotherapy RT . Patients and methods This retrospective series analyzed 166 patients under 18 years old treated from January 1985 to December 2003. Median age was 10 years range 2-18 . The male to female ratio was 2 3 1. Lymphonode enlargement was the most frequent clinical manifestation 68 and the time of symptom duration was less than 6 months in 55 of the patients. In histological analysis Nodular Sclerosis was the most prevalent .