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Báo cáo y học: "Fibromyalgia and sleep-disordered breathing: the missing link author’s response"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Fibromyalgia and sleep-disordered breathing: the missing link author’s response. | Available online http arthritis-research.eom content 10 6 409 Letter Fibromyalgia and sleep-disordered breathing the missing link -author s response Jean Eisinger Infomyalgies Unit Centre Hospitalier 83056 Toulon cedex France Corresponding author Jean Eisinger infomyalgies@orange.fr Published 25 November 2008 Arthritis Research Therapy 2008 10 409 doi 10.1186 ar2539 This article is online at http arthritis-research.com content 10 6 409 2008 BioMed Central Ltd See related letter by Martinez and Cassol http arthritis-research.com content 10 6 408 related review articles by Martinez-Lavin http arthritis-research.com content 9 4 216 and Staud http arthritis-research.com content 8 3 208 related research article by Vargas-Alarcón http arthritis-research.com content 9 5 R110 related editorial by Eisinger http arthritis-research.com content 9 4 105 and related letter by Felix and Fontenele http arthritis-research.com content 9 5 404 Fibromyalgia pathophysiology is a labyrinth where our understanding has grown from counting tender points to an evolving concept of subgroups and a countless variety of dysfunctional biochemical and metabolic interactions 1 . Sleep disorders have been reported in fibromyalgia patients 2 including daytime somnolence and tiredness and nonrestorative and fragmented sleep with higher occurrence of arousals often associated with breathing-related disturbances. Electroencephalogram findings exhibit alpha-delta sleep and a reduction of slow-wave sleep 2 3 . More sophisticated studies may identify upper airway resistance syndrome or obstructive sleep apnea-hypoapnea syndrome associated with increased risk for cardiovascular events 4 . Conflicting results have been reported on the prevalence of fibromyalgia observed in patients with sleep apnea it was significantly increased versus a control group according to Germanowicz 4 but was not according to Plantamura and colleagues 3 . It is noteworthy that Moldofsky 5 30 years ago demonstrated the induction of

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