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Báo cáo y học: "The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets. | Available online http arthritis-research.eom content 11 5 R152 Research article The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets Jade E Hollis-Moffatt1 Kerry A Rowley1 Amanda J Phipps-Green1 Marilyn E Merriman1 Nicola Dalbeth2 Peter Gow3 Andrew A Harrison4 John Highton5 Peter BB Jones2 Lisa K Stamp6 Pille Harrison7 B Paul Wordsworth7 and Tony R Merriman1 1 Department of Biochemistry University of Otago 710 Cumberland Street Dunedin 9054 New Zealand 2Department of Medicine University of Auckland 2 Park Road Auckland 1023 New Zealand 3Rheumatology Middlemore Hospital 100 Hospital Road Auckland 2025 New Zealand 4Department of Medicine University of Otago 23A Mein Street Wellington 6242 New Zealand 5Department of Medicine University of Otago 201 Great King Street Dunedin 9016 New Zealand 6Department of Medicine University of Otago 2 Riccarton Avenue Christchurch 8140 New Zealand 7Nuffield Department of Orthopaedics Nuffield Orthopaedic Centre Windmill Road Oxford OX3 7LD UK Corresponding author Jade E Hollis-Moffatt jade.hollis-moffatt@otago.ac.nz Received 18 May 2009 Revisions requested 15 Jun 2009 Revisions received 29 Sep 2009 Accepted 9 Oct 2009 Published 9 Oct 2009 Arthritis Research Therapy 2009 11 R152 doi 10.11 86 ar2828 This article is online at http arthritis-research.com content 11 5 R152 2009 Hollis-Moffatt et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Angiogenesis is an important process in the development of destructive synovial pannus in rheumatoid arthritis RA . The ITGAV gene encodes a cell cycle-associated antigen integrin avp 3 which plays a role in RA angiogenesis. Previously two independent studies identified an .