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Báo cáo y học: "Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan. | Tsai et al. Respiratory Research 2010 11 11 http respiratory-research.eom content 11 1 11 RESPIRATORY RESEARCH RESEARCH Open Access Household environmental tobacco smoke and risks of asthma wheeze and bronchitic symptoms among children in Taiwan Ching-Hui Tsai1 Jiun-Hau Huang2 Bing-Fang Hwang3 Yungling L Lee1 4 Abstract Background Although studies show that maternal smoking during pregnancy increases the risks of respiratory outcomes in childhood evidence concerning the effects of household environmental tobacco smoke ETS exposure remains inconsistent. Methods We conducted a population-based study comprised of 5 019 seventh and eighth-grade children in 14 Taiwanese communities. Questionnaire responses by parents were used to ascertain children s exposure and disease status. Logistic regression models were fitted to estimate the effects of ETS exposures on the prevalence of asthma wheeze and bronchitic symptoms. Results The lifetime prevalence of wheeze was 11.6 and physician-diagnosed asthma was 7.5 in our population. After adjustment for potential confounders in utero exposure showed the strongest effect on all respiratory outcomes. Current household ETS exposure was significantly associated with increased prevalence of active asthma ever wheeze wheeze with nighttime awakening and bronchitis. Maternal smoking was associated with the increased prevalence of a wide range of wheeze subcategories serious asthma and chronic cough but paternal smoking had no significant effects. Although maternal smoking alone and paternal smoking alone were not independently associated with respiratory outcomes joint exposure appeared to increase the effects. Furthermore joint exposure to parental smoking showed a significant effect on early-onset asthma OR 2.01 95 CI 1.00-4.02 but did not show a significant effect on late-onset asthma OR 1.17 95 CI 0.36-3.87 . Conclusion We concluded that prenatal and household ETS exposure had significant adverse effects on respiratory health in .