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Báo cáo y học: " Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a crosssectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a crosssectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project. | Callahan et al. Arthritis Research Therapy 2010 12 R46 http arthritis-research.eom content 12 2 R46 RESEARCH ARTICLE Open Access Limited educational attainment and radiographic and symptomatic knee osteoarthritis a crosssectional analysis using data from the Johnston County North Carolina Osteoarthritis Project 1.2.3 1 4 5 16 Leigh F Callahan 1 Jack Shreffler Bernadette C Siaton Charles G Helmick Britta Schoster Todd A Schwartz Jiu-Chiuan Chen7 Jordan B Renner8 Joanne M Jordan1 2 Abstract Introduction Applying a cross-sectional analysis to a sample of 2 627 African-American and Caucasian adults aged 45 years from the Johnston County Osteoarthritis Project we studied the association between educational attainment and prevalence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis. Methods Age- and race-adjusted associations between education and osteoarthritis outcomes were assessed by gender-stratified logistic regression models with additional models adjusting for body mass index knee injury smoking alcohol use and occupational factors. Results In an analysis of all participants low educational attainment 12 years was associated with higher prevalence of four knee osteoarthritis outcomes unilateral and bilateral radiographic and symptomatic osteoarthritis . Women with low educational attainment had 50 higher odds of having radiographic knee osteoarthritis and 65 higher odds of symptomatic knee osteoarthritis compared with those with higher educational attainment 12 years by using fully adjusted models. In the subset of postmenopausal women these associations tended to be weaker but little affected by adjustment for hormone replacement therapy. Men with low educational attainment had 85 higher odds of having symptomatic knee osteoarthritis by using fully adjusted models but the association with radiographic knee osteoarthritis was explained by age. Conclusions After adjustment for known risk factors educational attainment as an indicator of .