Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: "Cancer risks of dermatomyositis and polymyositis: a nationwide cohort study in Taiwan"

Không đóng trình duyệt đến khi xuất hiện nút TẢI XUỐNG

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Cancer risks of dermatomyositis and polymyositis: a nationwide cohort study in Taiwan. | Chen et al. Arthritis Research Therapy 2010 12 R70 http arthritis-research.eom content 12 2 R70 RESEARCH ARTICLE Open Access Career risks of dermatomyositis and polymyositis a nationwide cohort study in Taiwan Yi-Ju Chen21 2 Chun-Ying Wu23 4 5 Yu-Lin Huang 1 6 Chang-Bi Wang4 Jui-Lung Shen2 and Yun-Ting Chang 1 6 Abstract Introduction The association of idiopathic inflammatory myositis IIM and malignancies has been reported but rarely in Asian countries. Our aim was to investigate the risk of cancer among IIM patients without a prior history of malignancies in Taiwan. Methods We conducted a nationwide cohort study of 1 012 patients with dermatomyositis DM and 643 patients with polymyositis PM but without prior history of malignancies utilizing the National Health Insurance Database from 1997 to 2007. Standardized incidence ratios SIRs of cancers were analyzed. Results A total of 95 cancers 9.4 in DM and 33 cancers 4.4 in PM were identified. Overall cancer risk was significantly elevated in DM patients SIR 5.11 95 confidence interval CI 5.01 to 5.22 and PM patients SIR 2.15 95 CI 2.08 to 2.22 . Most cancers were detected in the first year of observation. The risk of cancer decreased with observation time yet remained elevated compared with the general population in both study groups after 5 years of follow-up. DM was associated with sustained elevated risk of cancers in every age group whereas the risk of cancer in PM was highest in younger patients and decreased with age. DM patients were at the greatest risk of cancers of the nasopharynx lungs and hematopoietic malignancies. Conclusions Patients with IIM are at increased risk for cancer and should receive age-appropriate and gender-appropriate malignancy evaluations with additional assessment for nasopharyngeal lung and hematologic malignancy following diagnosis and with continued vigilance for development of cancers in follow-up. Introduction The association of malignancies with dermatomyositis DM or polymyositis

TÀI LIỆU LIÊN QUAN
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.