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Báo cáo khoa học: "Acute Phase Proteins in Response to Dictyocaulus viviparus Infection in Calves"

Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: Acute Phase Proteins in Response to Dictyocaulus viviparus Infection in Calves. | Acta vet. scand. 2004 45 79-86. Acute Phase Proteins in Response to Dictyocaulus viviparus Infection in Calves By C. Gảnheim1 J. Hoglund2 and K. Persson Waller3 Department of Obstetrics and Gynaecology Centre for Reproductive Biology Swedish University of Agricultural Sciences 2Department of Parasitology SWEPAR National Veterinary Institute and Swedish University of Agricultural Sciences and 3Department of Ruminant and Porcine Diseases National Veterinary Institute Uppsala Sweden Gânheim C Hoglund J Persson Waller K Acute phase proteins in response to Dic-tyocaulus viviparus infection in calves. Acta vet. scand. 2004 45 79-86. - Three experiments were carried out to examine the acute phase response as measured by the acute phase proteins APP haptoglobin serum amyloid A SAA and fibrinogen in calves infected with lungworm Dictyocaulus vivparus. In addition eosinophil counts were analysed. Three different dose models were used in 3 separate experiments I 250 D. viviparus infective third stage larvae L3 once daily for 2 consecutive days II 100 D. viviparus L3 once daily for 5 consecutive days and III 2000 L3 once. All 3 dose regimes induced elevated levels of haptoglobin SAA and fibrinogen although there was considerable variation both between and within experiments. A significant increase was observed in all 3 APP at one or several time points in experiment I and III whereas in experiment II the only significant elevation was observed for fibrinogen at one occasion. The eosinophil numbers were significantly elevated in all 3 experiments. The results show that lungworm infection can induce an acute phase response which can be monitored by the selected APP. Elevated APP levels in combination with high numbers of eosinophils in an animal with respiratory disease may be used as an indicator of lung worm infection and help the clinician to decide on treatment. However high numbers of eosinophils and low levels of APP do not exclude a diagnosis of lungworm. Thus lungworm .