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Báo cáo y học: " Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation. | Respiratory Research BioMed Central Research Open Access Lung development in laminin y2 deficiency abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation Nguyet M Nguyen1 Leena Pulkkinen3 Jessica A Schlueter1 Guerrino Meneguzzi4 Jouni Uitto5 6 and Robert M Senior 1 2 Address Department of Internal Medicine Washington University School of Medicine St. Louis Missouri USA 2Department of Cell Biology Physiology Washington University School of Medicine St. Louis Missouri USA 3Department of Clinical Nutrition University of Kuopio Kuopio Finland 4INSERM U634 School of Medicine University of Nice-Sophia Antipolis Nice France 5Department of Dermatology and Cutaneous Biology Jefferson Medical College Thomas Jefferson University Philadelphia Pennsylvania USA and 6Department of Biochemistry and Molecular Biology Jefferson Medical College Thomas Jefferson University Philadelphia Pennsylvania USA Email Nguyet M Nguyen - nnguyen@im.wustl.edu Leena Pulkkinen - leena.pulkkinen@uku.fi Jessica A Schlueter - jschluet@im.wustl.edu Guerrino Meneguzzi - guerrino.meneguzzi@unice.fr Jouni Uitto - jouni.uitto@jefferson.edu Robert M Senior - rsenior@im.wustl.edu Corresponding author Published 16 February 2006 Received 29 November 2005 Respiratory Research 2006 7 28 doi 10.1186 1465-9921 -7-28 Accepted 16 February 2006 This article is available from http respiratory-research.cOm content 7 1 28 2006 Nguyen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Laminin y2 Lamc2 one of the polypeptides in laminin-332 laminin-5 is prominent in the basement membrane of alveolar walls and airways of developing and adult lung. Laminins are important for lung morphogenesis and based on its .