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Báo cáo y học: " Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons. | Respiratory Research BioMed Central Research Open Access Tuberculosis contact investigation with a new specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons R Diel 1 A Nienhaus2 C Lange3 K Meywald-Walter4 M ForRbohm5 and T Schaberg6 Address 1School of Public Health University of Dusseldorf Germany institution for statutory accident insurance and prevention in the health and welfare services Hamburg Germany 3Research Center Borstel Division of Clinical Infectious Diseases Germany 4Public Health Department Hamburg-Mitte Germany 5Public Health Department Wiesbaden Germany and 6Center of Pneumology Deaconess Hospital Rotenburg Wumme Germany Email R Diel - Roland.Diel@uni-duesseldorf.de ANienhaus - Albert.Nienhaus@bgw-online.de C Lange - clange@fz-borstel.de K Meywald-Walter - karen.meywald-walter@hamburg-mitte.hamburg.de M ForRbohm - michael.forssbohm@wiesbaden.de T Schaberg - Schaberg@diako-online.de Corresponding author Published 17 May 2006 Received 03 January 2006 Respiratory Research 2006 7 77 doi 10.1186 1465-9921 -7-77 Accepted 17 May 2006 This article is available from http respiratory-research.com content 7 1 77 2006 Diel et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background BCG-vaccination can confound tuberculin skin test TST reactions in the diagnosis of latent tuberculosis infection. Methods We compared the TST with a Mycobacterium tuberculosis specific whole blood interferon-gamma assay QuantiFERON -TB-Gold In Tube QFT-G during ongoing investigations among close contacts of sputum smear positive source cases in Hamburg Germany. Results During a 6-month period 309 contacts mean age 28.5 10.5 years from a total of 15 source cases underwent both .