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Báo cáo y học: "The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients. | Critical Care December 2001 Vol 5 No 6 Cook et al. Research article The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients Deborah J Cook 1 Lauren E Griffith Stephen D Walter1- Gordon H Guyatt 1 Maureen O Meade Daren K Heyland Ann Kirby and Michael Tryba for the Canadian Critical Care Trials Group Department of Medicine McMaster University Hamilton Ontario Canada Department of Clinical Epidemiology Biostatistics McMaster University Hamilton Ontario Canada Department of Medicine Queen s University Kingston Ontario Canada Department of Critical Care University of Calgary Calgary Alberta Canada Department of Anesthesia University of Bochum Bochum Germany Correspondence Deborah J Cook debcook@mcmaster.ca Received 31 January 2001 Revisions requested 5 September 2001 Revisions received 8 September 2001 Accepted 20 September 2001 Published 9 October 2001 Critical Care 2001 5 368-375 2001 Cook et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Objective To estimate the mortality and length of stay in the intensive care unit ICU attributable to clinically important gastrointestinal bleeding in mechanically ventilated critically ill patients. Design Three strategies were used to estimate the mortality attributable to bleeding in two multicentre databases. The first method matched patients who bled with those who did not matched cohort using duration of ICU stay prior to the bleed each of six domains of the Multiple Organ Dysfunction Score MODS measured 3 days prior to the bleed APACHE II score age admitting diagnosis and duration of mechanical ventilation. The second approach employed Cox proportional hazards regression to match bleeding and non-bleeding patients model-based matched cohort . The third method instead of matching derived estimates based on regression modelling using the entire population regression method . Three parallel analyses were .