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Báo cáo khoa học: "Prevalence of four different subgenotypes of genotype 4 hepatitis E virus among swine in the Shanghai area of China"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Prevalence of four different subgenotypes of genotype 4 hepatitis E virus among swine in the Shanghai area of China. | Acta Veterinaria Scandinavica BioMed Central Research Prevalence of four different subgenotypes of genotype 4 hepatitis E virus among swine in the Shanghai area of China Yijia Yan Wen Zhangt Quan Shen Li Cui and Xiuguo Hua Address Shanghai Key laboratory of Veterinary Biotechnology School of Agriculture and Biology Shanghai JiaoTong University 800 Dongchuan Road Shanghai 200240 PR China Email Yijia Yan - y_yan11@sjtu.edu.cn Wen Zhang - z0216wen@sjtu.edu.cn Quan Shen - Shenquanfly@yahoo.com Li Cui - lcui@sjtu.edu.cn Xiuguo Hua - hxg@sjtu.edu.cn Corresponding author fEqual contributors Open Access Published 31 May 2008 Received 19 January 2008 Acta Veterinaria Scandinavian 2008 50 12 doi 10.1186 1751-0147-50-12 Accepted 3 1 May 2008 This article is available from http www.actavetscand.cOm content 50 l l2 2008 Yan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Hepatitis E virus HEV is a zoonotic pathogen of which swine was reported as major reservoirs. HEV has been divided into 4 different genotypes according to phylogenetic analysis. Recent reports showed that genotype 4 HEV is freely transmitted between humans and swine in eastern China including Shanghai area. This paper investigated the recent infection status of HEV among swine population of Shanghai area in China. Methods 480 swine faecal specimens were collected from 23 farms which distribute all over Shanghai from September to November 2007 and tested for the presence of HEV RNA by the polymerase chain reaction PCR . Results Our results showed that 26.1 6 23 of the swine farms were positive for HEV RNA and the positive rate of the six farms were ranged from 9.1 to 33.3 . The HEV RNA positive rate for total samples were 5 24 480 . The resulted