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Báo cáo y học: " Oestradiol-17b plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Oestradiol-17b plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama). | Cavilla et al. Acta Veterinaria Scandinavica 2010 52 13 http www.actavetscand.eom content 52 1 13 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Oestradiol-17p plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas Lama glama María V Cavilla Carolina P Bianchi Marcelo A Aba Abstract Background Llamas Lama glama are induced ovulators and the process of ovulation depends on dominant follicular size. In addition a close relationship between behavioural estrus and ovulation is not registered in llamas. Therefore the exogenous control of follicular development with hormones aims to predict the optimal time to mate. Oestradiol-17b E2 and its esters are currently used in domestic species including camelids in synchronization treatments. But in llamas there is no reports regarding the appropriate dosages to be used and most protocols have been designed by extrapolation from those recommended for other ruminants. The aim of the present study was to characterize plasma E2 concentrations in intact female llamas following a single intramuscular i.m. injection of two oestradiol esters oestradiol benzoate EB and oestradiol cypionate ECP . Methods Twelve non pregnant and non lactating sexually mature llamas were i.m. injected on day 0 with 2.5 mg of EB EB group n 6 or ECP ECP group n 6 . Blood samples were collected immediately before injection at 1 6 12 24 h after treatment and then daily until day 14 post injection. Changes in hormone concentrations with time were analyzed in each group by analysis of variance ANOVA using a repeated measures within-SS design. Plasma E2 concentrations and area under the concentration-time curve AUC values were compared between groups by ANOVA. In all cases a Least-Significant Difference test LSD was used to determine differences between means. Hormonal and AUC data are expressed as mean S.E.M. Results Peak plasma E2 concentrations were achieved earlier and were higher in EB group than