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Báo cáo y học: "Glucose–insulin–potassium infusion in sepsis and septic shock: no hard evidence yet"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài:Glucose–insulin–potassium infusion in sepsis and septic shock: no hard evidence yet. | Available online http ccforum.eom content 7 1 13 Commentary Glucose-insulin-potassium infusion in sepsis and septic shock no hard evidence yet Iwan CC van der Horst1 Jack JM Ligtenberg2 Henk JG Bilo3 Felix Zijlstra4 and Rijk OB Gans5 1 Resident Department of Cardiology Isala Clinics location Weezenlanden Zwolle The Netherlands 2Internist-Endocrinologist Intensive Respiratory Care Unit of the Department of Internal Medicine University Hospital Groningen Groningen The Netherlands 3Internist-Nephrologist Department of Internal Medicine Isala Clinics location Weezenland Zwolle The Netherlands 4Cardiologist Department of Cardiology Isala Clinics location Weezenlanden Zwolle The Netherlands 5Professor Department of Internal Medicine University Hospital Groningen Groningen The Netherlands Correspondence Iwan CC van der Horst iwanouk@hotmail.com Published online 9 October 2002 Critical Care 2003 7 13-15 DOI 10.1186 cc1832 This article is online at http ccforum.com content 7 1 13 2003 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract There is no hard evidence yet for a positive effect of glucose-insulin-potassium infusion in sepsis septic shock or burn patients. Each individual element of the glucose-insulin-potassium regimen and eventually euglycaemia should theoretically be beneficial. At present evidence exists only for reduced mortality with strict metabolic treatment i.e. blood glucose levels of 4.4-6.1 mmol l in critically ill patients admitted to surgical intensive care units and for better metabolic regulation i.e. blood glucose levels of 7.0-10.0 mmol l in patients with hyperglycaemia and or diabetes mellitus and in patients without signs of heart failure i.e. Killip class I during acute myocardial infarction. Keywords euglycaemia glucose insulin myocardial infarction sepsis septic shock Recently in this journal Dr Undurti Das 1 suggested that treatment of sepsis septic shock and burns should also include infusion of glucose-insulin-potassium .