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Báo cáo y học: "Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Pro/con clinical debate: Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis. | Available online http ccforum.eom content 7 5 351 Review Pro con clinical debate Antibiotics are important in the management of patients with pancreatitis with evidence of pancreatic necrosis Graham Ramsay1 Paul Breedveld2 Lorne H Blackbourne3 and Stephen M Cohn4 1 Professor and Chief of Intensive Care and Accident Department University Hospital Maastricht The Netherlands 2Trauma Surgeon and Intensivist University Hospital Maastricht The Netherlands 3Fellow in Trauma and Surgical Critical Care University of Miami School of Medicine Ryder Trauma Center Miami FL USA 4The Robert Zeppa Professor of Surgery Chief Divisions of Trauma and Surgical Critical Care University of Miami School of Medicine and Medical Director Ryder Trauma Center Miami FL USA Correspondence Critical Care Editorial Office editorial@ccforum.com Published online 17 March 2003 Critical Care 2003 7 351-353 DOI 10.1186 cc2165 This article is online at http ccforum.com content 7 5 351 2003 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Pancreatitis is not an infrequent diagnosis in patients admitted to the intensive care unit. Prolonged stays intense resource utilization and high morbidity mortality are commonplace in such patients. Management for the most part is supportive with the surgical team keeping close watch to intervene as the need arises. Over the past few decades there has been considerable debate regarding the usefulness of systemic antibiotics to prevent infectious complications in patients with evidence of pancreatic necrosis. In the present article of Critical Care two expert groups debate the two sides of this contentious antibiotic issue. Keywords antibiotic prophylaxis critical care multiorgan failure pancreatic necrosis pancreatitis The scenario A 29-year-old male develops severe pancreatitis presumably as a result of heavy alcohol intake. He is admitted to the hospital ward for management but becomes hypoxic over the first 24 hours requiring intubation and .