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Báo cáo khoa học: "Changes in pulse pressure variability during cardiac resynchronization therapy in mechanically ventilated patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Changes in pulse pressure variability during cardiac resynchronization therapy in mechanically ventilated patients. | Available online http ccforum.eom content 11 2 R46 Research Changes in pulse pressure variability during cardiac resynchronization therapy in mechanically ventilated patients Cornelius Keyl1 Jochem Stockinger2 Sven Laule1 Klaus Staier1 Jochen Schiebeling-Romer2 and Christoph Wiesenack3 1 Department of Anesthesiology Heart Centre Bad Krozingen Suedring 15 79189 Bad Krozingen Germany 2Department of Rhythmology Heart Centre Bad Krozingen Suedring 15 79189 Bad Krozingen Germany 3Department of Anesthesiology University Hospital Regensburg Franz-Josef-Strauss-Allee 11 93042 Regensburg Germany Corresponding author Cornelius Keyl cornelius.keyl@herzzentrum.de Received 13 Jan 2007 Revisions requested 27 Feb 2007 Revisions received 20 Mar 2007 Accepted 19 Apr 2007 Published 19 Apr 2007 Critical Care 2007 11 R46 doi 10.1186 cc5779 This article is online at http ccforum.com content 11 2 R46 2007 Keyl et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The respiratory variation in pulse pressure PP has been established as a dynamic variable of cardiac preload which indicates fluid responsiveness in mechanically ventilated patients. The impact of acute changes in cardiac performance on respiratory fluctuations in PP has not been evaluated until now. We used cardiac resynchronization therapy as a model to assess the acute effects of changes in left ventricular performance on respiratory PP variability without the need of pharmacological intervention. Methods In 19 patients undergoing the implantation of a biventricular pacing defibrillator device under general anesthesia dynamic blood pressure regulation was assessed during right ventricular and biventricular pacing in the frequency domain power .