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Báo cáo khoa học: " Red blood cell transfusions and the risk of acute respiratory distress syndrome among the critically ill: a cohort study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Red blood cell transfusions and the risk of acute respiratory distress syndrome among the critically ill: a cohort study. | Available online http ccforum.eom content 11 3 R63 Research Red blood cell transfusions and the risk of acute respiratory distress syndrome among the critically ill a cohort study Marya D Zilberberg1 Chureen Carter2 Patrick Lefebvre3 Monika Raut2 Francis Vekeman3 Mei Sheng Duh4 and Andrew F Shorr5 1School of Public Health and Health Sciences University of Massachusetts Amherst P.O. Box 303 Goshen MA 01032 USA 2Ortho Biotech Clinical Affairs LLC 430 Route 22 East Bridgewater NJ 08807 USA 3Groupe d analyse 1080 Beaver Hall Hill Suite 1810 Montreal Quebec H2Z 1S8 Canada 4Analysis Group 111 Huntington Avenue Tenth Floor Boston MA 021 99 USA 5Washington Hospital Center 110 Irving Street NW Washington DC 20010 USA Corresponding author Marya D Zilberberg mzilberb@schoolph.umass.edu Received 28 Feb 2007 Revisions requested 29 Mar 2007 Revisions received 11 Apr 2007 Accepted 6 Jun 2007 Published 6 Jun 2007 Critical Care 2007 11 R63 doi 10.1186 cc5934 This article is online at http ccforum.com content 11 3 R63 2007 Zilberberg et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Recent data indicate that transfusion of packed red blood cells pRBCs may increase the risk for the development of acute respiratory distress syndrome ARDS in critically ill patients. Uncertainty remains regarding the strength of this relationship. Methods To quantify the association between transfusions and intensive care unit ICU -onset ARDS we performed a cohort study within Crit a multicenter prospective observational study of transfusion practice in the ICU which enrolled 4 892 critically ill patients in 284 ICUs in the United States. Diagnostic criteria for ARDS were prospectively defined and we focused on subjects .