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Báo cáo y học: "Antifungal prophylaxis in critically ill patient"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Antifungal prophylaxis in critically ill patients. | Available online http ccforum.eom content 12 3 420 Letter Antifungal prophylaxis in critically ill patients Luciano Silvestri1 Durk F Zandstra2 Hendrick KF van Saene3 Andy J Petros4 Sujatha Thyagarajan5 Miguel A de la Cal6 and Corrado Thomann1 1 Department of Emergency Unit of Anaesthesia and Intensive Care Presidio Ospedaliero Via Vittorio Veneto 171 34170 Gorizia Italy 2Department of Intensive Care Onze Lieve Vrouwe Gasthuis Oosterpark 9 1091 AC Amsterdam The Netherlands 3Department of Medical Microbiology University of Liverpool Duncan Building Daulby Street Liverpool L69 3GA UK 4Paediatric and Neonatal Intensive Care Unit Great Ormond Street Children s Hospital Great Ormond Street London WC1N 3JH UK 5Department of Intensive Care Alder Hey Children s Hospital Eaton Road Liverpool L12 2AP UK intensive Care Unit University Hospital Carretera de Toledo km 12 500 28905 Getafe Madrid Spain Corresponding author Luciano Silvestri lucianosilvestri@yahoo.it Published 13 June 2008 This article is online at http ccforum.com content 12 3 420 2008 BioMed Central Ltd Critical Care 2008 12 420 doi 10.1186 cc6906 See related research by van Till et al. http ccforum.com content 11 6 R126 We congratulate van Till and colleagues on their review showing that selective decontamination of the digestive tract SDD is more effective than single-drug prophylaxis SAP in reducing yeast colonisation infection and mortality 1 . The authors claimed that their review differs from our earlier review which included paediatric or liver transplant patients. In our review a subgroup analysis was performed in both selected and unselected populations and demonstrated a significant reduction in yeast carriage and infection in unselected critically ill patients 2 . van Till and colleagues assessed yeast colonisation lumping together positive yeast cultures obtained from sputum stool urine and or wound 1 . The majority of SDD trials reported positive yeast cultures obtained from surveillance cultures of