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Báo cáo y học: "Extracorporeal life support for severe drug-induced cardiotoxicity: a promising therapeutic choice"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Extracorporeal life support for severe drug-induced cardiotoxicity: a promising therapeutic choice. | Available online http ccforum.eom content 13 5 187 Commentary Extracorporeal life support for severe drug-induced cardiotoxicity a promising therapeutic choice Hutan Ashrafian and Thanos Athanasiou Department of Biosurgery and Surgical Technology Imperial College London Imperial College Healthcare NHS Trust at St Mary s Hospital Praed Street London W2 1NY United Kingdom Corresponding author Thanos Athanasiou t.athanasiou@imperial.ac.uk Published 24 September 2009 This article is online at http ccforum.com content 13 5 187 2009 BioMed Central Ltd Critical Care 2009 13 187 doi 10.1186 cc8046 See related research by Daubin et al. http ccforum.com content 13 4 R138 Abstract Drug-induced cardiovascular failure is an acute condition that is associated with significant healthcare consequences. Antidotes and supportive treatments are the initial measures to manage cardiotoxicity but if severe drug-induced cardiotoxicity develops usually as cardiovascular shock or cardiac arrest then circulatory assistance may have an important role in the therapeutic algorithm. A number of circulatory assistance techniques have been increasingly employed to treat severe drug-induced cardiotoxicity. These include extracorporeal membrane oxygenation intra-aortic balloon pumping and standard cardiopulmonary bypass. Recently extracorporeal life support ECLS has been developed to provide percutaneous cardiopulmonary support peripherally without the need for sternotomy. ECLS can provide successful treatment of severe drug-induced cardiotoxicity in selected cases. This technique may be associated with complications of limb ischaemia haemorrhage and embolism. An increased consideration of ECLS within the context of rigorous clinical studies and strong evidence can add to its future use for severe drug-induced cardiotoxicity. In their recent study Daubin and colleagues 1 highlight the management of drug-induced cardiotoxicity. Cardiovascular failure as a result of drug poisoning is an acute .