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Báo cáo y học: "Quality of life in the five years after intensive care: a cohort study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Quality of life in the five years after intensive care: a cohort study. | Cuthbertson et al. Critical Care 2010 14 R6 http ccforum.eom content 14 1 R6 c CRITICAL CARE RESEARCH Open Access Quality of life in the five years after intensive care a cohort study Brian H Cuthbertson1 Siân Roughton2 David Jenkinson3 Graeme MacLennan3 Luke Vale2 4 Abstract Introduction Data on quality of life beyond 2 years after intensive care discharge are limited and we aimed to explore this area further. Our objective was to quantify quality of life and health utilities in the 5 years after intensive care discharge. Methods A prospective longitudinal cohort study in a University Hospital in the UK. Quality of life was assessed from the period before ICU admission until 5 years and quality adjusted life years calculated. Results 300 level 3 intensive care patients of median age 60.5 years and median length of stay 6.7 days were recruited. Physical quality of life fell to 3 months P 0.003 rose back to pre-morbid levels at 12 months then fell again from 2.5 to 5 years after intensive care P 0.002 . Mean physical scores were below the population norm at all time points but the mean mental scores after 6 months were similar to those population norms. The utility value measured using the EuroQOL-5D quality of life assessment tool EQ-5D at 5 years was 0.677. During the five years after intensive care unit the cumulative quality adjusted life years were significantly lower than that expected for the general population P 0.001 . Conclusions Intensive care unit admission is associated with a high mortality a poor physical quality of life and a low quality adjusted life years gained compared to the general population for 5 years after discharge. In this group critical illness associated with ICU admission should be treated as a life time diagnosis with associated excess mortality morbidity and the requirement for ongoing health care support. Introduction Intensive care management is associated with significant morbidity and mortality as well as a huge health care .