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Báo cáo y học: "Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection. | Namendys-Silva et al. Critical Care 2010 14 407 http ccforum.eom content 14 2 407 CRITICAL CARE LETTER L_ Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection Silvio A Namendys-Silva Marisol Hernandez-Garay 2 and Eduardo Rivero-Sigarroa3 See related research by Relloetal. http ccforum.com content 3 5 R 48 We read with interest the study reported by Rello and colleagues 1 . The authors described the first 32 documented patients with pandemic influenza A H1N1 PIAH1N1 virus infection hospitalized in an intensive care unit ICU in Spain. Twenty-four patients 75.0 had refractory hypoxemia and required advanced mechanical ventilation. Eight patients 33.3 received noninvasive mechanical ventilation at ICU admission. Six of these patients 75 required further orotracheal intubation and invasive mechanical ventilation and two 33 died. Non-invasive ventilation NIV is not recommended for patients with PIAH1N1 virus infection complicated by pneumonia acute lung injury ALI or acute respiratory distress syndrome ARDS because although NIV temporarily improves oxygenation and reduces the work of breathing in these patients it does not necessarily change the natural disease course. On the other hand NIV may increase the risk of respiratory pathogen transmission 2 and there is not enough evidence to support the treatment of ALI ARDS with NIV. To date three studies have suggested that NIV has not been successful in critically ill patients with hypoxemic respiratory failure attributable to PIAH1N1 virus infection 1 3 4 . In these studies a total of 76 patients received NIV but 64 84.2 of these patients required subsequent intubation and invasive ventilation. Considering the high failure rate of NIV therapy in patients with PIAH1N1 virus infection and ALI ARDS the treatment of ARDS associated with the PIAH1N1 virus infection should be based upon published evidence-based guidelines for sepsis-associated ARDS. Standard .

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