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Báo cáo y học: "Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays. | Researc h Open Access Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays Samuel P Hazen Felix Naef Tom QuiseT Joshua M Gendron Huaming Chen Joseph R Ecker Justin O Borevitz and Steve A Kay Addresses Section of Cell and Developmental Biology University of California San Diego Gilman Drive La Jolla CA 92093-0130 USA. School of Life Science Ecole Polytechnique Federale de Lausanne EPFL CH-1015 Lausanne Switzerland. Plant Biology Laboratory and Genome Analysis Laboratory The Salk Institute for Biological Studies N. Torrey Pines Road La Jolla CA 92037 USA. Department of Evolution and Ecology University of Chicago E. 57th Street Chicago IL 60637 USA. Biology Department University of Massachusetts N. Pleasant Street Amherst MA 01003 USA. Correspondence Steve A Kay. Email skay@ucsd.edu Published II February 2009 Genome Biology 2009 10 RI7 doi I0.II86 gb-2009- I0-2-rI7 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 I0 2 RI7 Received 5 August 2008 Revised 9 December 2008 Accepted II February 2009 2009 Hazen et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Organisms are able to anticipate changes in the daily environment with an internal oscillator know as the circadian clock. Transcription is an important mechanism in maintaining these oscillations. Here we explore using whole genome tiling arrays the extent of rhythmic expression patterns genome-wide with an unbiased analysis of coding and noncoding regions of the Arabidopsis genome. Results As in previous studies we detected a circadian rhythm for approximately 25 of the protein coding genes in the genome. With an unbiased interrogation of the .