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Báo cáo y học: " SEPALLATA3: the 'glue' for MADS box transcription"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: SEPALLATA3: the 'glue' for MADS box transcription. | Open Access Researc h SEPALLATA3 the glue for MADS box transcription factor complex formation Richard GH ImminkH Isabella AN TonacoH Stefan de Folter Anna Shchennikova Aalt DJ van Dijk Jacqueline Busscher-Lange Jan W Borsf and Gerco C Angenent Addresses Plant Research International Bioscience Droevendaalsesteeg 1 Wageningen the Netherlands. Wageningen University Microspectroscopy Centre Department of Biochemistry Dreijenlaan 3 Wageningen the Netherlands. Current address National Laboratory of Genomics for Biodiversity Langebio Centro de Investigation y de Estudios Avanzados del Instituto Politécnico Nacional CINVESTAV-IPN Campus Guanajuato CP 36821 Irapuato Guanajuato Mexico. Current address Center Bioengineering RAS prospect 60-letia Oktyabrya 7 korp. 1 117321 Moscow Russia. H These authors contributed equally to this work. Correspondence Richard GH Immink. Email richard.immink@wur.nl Published 25 February 2009 Genome Biology 2009 10 R24 doi 10.1186 gb-2009- 10-2-r24 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 10 2 R24 Received 1 October 2008 Revised 16 December 2008 Accepted 25 February 2009 2009 Immink et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Plant MADS box proteins play important roles in a plethora of developmental processes. In order to regulate specific sets of target genes MADS box proteins dimerize and are thought to assemble into multimeric complexes. In this study a large-scale yeast three-hybrid screen is utilized to provide insight into the higher-order complex formation capacity of the Arabidopsis MADS box family. SEPALLATA3 SEP3 has been shown to mediate complex formation and therefore special attention is