Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: " Phylogenetic classification of Escherichia coli O157:H7 strains of human and bovine origin using a novel set of nucleotide polymorphisms"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Phylogenetic classification of Escherichia coli O157:H7 strains of human and bovine origin using a novel set of nucleotide polymorphisms | Open Access Researc h Phylogenetic classification of Escherichia coli O157 H7 strains of human and bovine origin using a novel set of nucleotide polymorphisms Michael L Clawson James E KeenH Timothy PL Smith Lisa M Durso Tara G McDaneld Robert E Mandrell Margaret A Davis and James L Bono Addresses United States Department of Agriculture USDA Agricultural Research Service ARS US Meat Animal Research Center USMARC State Spur 18D Clay Center NE 68933 USA. USDA ARS Western Regional Research Center Buchanan St Albany CA 94710 USA. Washington State University Department of Pathology Bustad Hall Pullman WA 99164-7040 USA. Current address University of Nebraska Great Plains Veterinary Educational Center Clay Center NE 68933 USA. H These authors contributed equally to this work. Correspondence James L Bono. Email jim.bono@ars.usda.gov Published 22 May 2009 Genome Biology 2009 10 R56 doi l0.ll86 gb-2009- l0-5-r56 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 l0 5 R56 Received 21 January 2009 Revised 20 March 2009 Accepted 22 May 2009 2009 Clawson et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Cattle are a reservoir of Shiga toxin-producing Escherichia coli Ol57 H7 STEC O157 and are known to harbor subtypes not typically found in clinically ill humans. Consequently nucleotide polymorphisms previously discovered via strains originating from human outbreaks may be restricted in their ability to distinguish STEC Ol57 genetic subtypes present in cattle. The objectives of this study were firstly to identify nucleotide polymorphisms in a diverse sampling of human and bovine STEC Ol57 strains secondly to classify strains of either bovine or human