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Dermatology therapy essentials - part 5

Nghĩa của từ bịnh lở của ngựa (s); morve nhi chùy (bệnh ngựa); Whitmore bệnh (melioidosis) bệnh Định nghĩa liên quan được sản xuất bởi các vi khuẩn của các loài Burkholderia, được gram âm thanh đại lý bệnh sinh gây bệnh | Glanders and melioidosis 257 Differential diagnosis Condyloma acuminata squamous cell carcinoma Therapy Surgical excision interferon References Kanik AB Lee J Wax F Bhawan J 1997 Penile verrucous carcinoma in a 37-year-old circumcised man. Journal of the American Academy of Dermatology 37 2 Pt 2 329-33i Giant condylomata acuminata Of Buschke and Lowenstein Giant condyloma of Buschke and Lowenstein Giant follicle Dilated pore Giant hemangioma syndrome Kasabach-Merritt syndrome Giant malignant condyloma Giant condyloma of Buschke and Lowenstein Gingivitis desquamative Desquamative gingivitis I--------------------------------------- Glanders and melioidosis Synonym s Farcy morve malleus glanders Whitmore disease melioidosis Definition Related diseases produced by bacteria of the Burkholderia species which are gram-negative rods Pathogenesis Causative agent of Glanders Burkholderia mallei primarily a disease of animals such as horses mules and donkeys once in the host synthesis and release of certain toxins occur melioidosis caused by the bacterium Burkholderia pseudomallei organism distributed widely in the soil and water of the tropics and spread to humans through direct contact with a contaminated source Clinical manifestation Similar clinical syndrome in both diseases. Localized form bacteria enter the skin through a laceration or abrasion local infection with ulceration and regional lymphadenopathy incubation period 1-5 days bacteria that enter the host through mucous membranes sometimes cause increased mucus production in the affected areas Pulmonary form occurs when bacteria are aerosolized and enter respiratory tract via inhalation or hematogenous spread with inhalational melioidosis cutaneous abscesses may develop septicemia when bacteria disseminated in the bloodstream in glanders usually fatal within 7-10 days Chronic form multiple abscesses affecting the liver spleen skin or muscles Differential diagnosis Anthrax plague tuberculosis atypical mycobacterial .