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báo cáo khoa học: " Lumbar disc herniation in three patients with cystic fibrosis: a case series"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Lumbar disc herniation in three patients with cystic fibrosis: a case series | Denne et al. Journal of Medical Case Reports 2011 5 440 http www.jmedicalcasereports.eom content 5 1 440 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Lumbar disc herniation in three patients with cystic fibrosis a case series 1 1 1 2 31 Christian Denne Anna E Vogl-Voswinckel Harald Wurmser Marc Steinborn Manfred Spaeth Armin Gruebl and Stefan Burdach1 Abstract Introduction To date lumbar disc herniation has not been reported in the context of cystic fibrosis even though back pain and musculoskeletal problems are very common in patients with cystic fibrosis. Case presentation We report on three patients with cystic fibrosis who experienced lumbar disc herniation in the course of their disease at ages 19 to 21 years a 22-year-old Caucasian man a 23-year-old Caucasian man and a 21-year-old Caucasian woman . Our third patient eventually died because of her deteriorated pulmonary situation which was influenced by the lumbar disc herniation as it was not possible for her to perform pulmonary drainage techniques properly because of the pain. Conclusions Lumbar disc herniation can lead to a vicious cycle for patients with cystic fibrosis as it may promote pulmonary infections. This report highlights the need to investigate patients correctly. Introduction Cystic fibrosis CF is a lethal chronic pulmonary disease with recurrent acute infective exacerbations inevitably leading to progressive bronchiectasis and combined ventilatory disorders 1 . With the improved survival rates in recent decades CF may also be commonly associated with relevant painful conditions caused by complications of the illness and also by therapy itself which may cause additional suffering 2 3 . Back pain is a chief complaint in patients with cystic fibrosis 4 . It is often due to vertebral fractures as a consequence of a decreased bone mineral density due to use of steroids 5 . Rheumatoid arthritis spondyloarthropathies and posture abnormalities such as kyphosis have also been reported in