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Báo cáo khoa hoc:" Investigating the complexity of respiratory patterns during the laryngeal chemoreflex"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Investigating the complexity of respiratory patterns during the laryngeal chemoreflex | Journal of NeuroEngineering and Rehabilitation BioMed Central Research Investigating the complexity of respiratory patterns during the laryngeal chemoreflex Andrei Dragomir1 Yasemin Akay1 Aidan K Curran2 and Metin Akay 1 Open Access Address Harrington Department of Bioengineering Ira A. Fulton School of Engineering Arizona State University Tempe AZ 85287 USA and 2Department of Physiology Dartmouth Medical School NH 03756 USA Email Andrei Dragomir - Andrei.Dragomir@asu.edu Yasemin Akay - Yasemin.Akay@asu.edu Aidan K Curran - Aidan.Curran@spcorp.com Metin Akay - Metin.Akay@asu.edu Corresponding author Published 20 June 2008 Received 20 December 2007 Journal of NeuroEngineering and Rehabilitation 2008 5 17 doi 10.1186 1743-0003-5-17 Accepted 20 June 2008 This article is available from http www.jneuroengrehab.com content 5 1 17 2008 Dragomir et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The laryngeal chemoreflex exists in infants as a primary sensory mechanism for defending the airway from the aspiration of liquids. Previous studies have hypothesized that prolonged apnea associated with this reflex may be life threatening and might be a cause of sudden infant death syndrome. Methods In this study we quantified the output of the respiratory neural network the diaphragm EMG signal during the laryngeal chemoreflex and eupnea in early postnatal 3-10 days piglets. We tested the hypothesis that diaphragm EMG activity corresponding to reflex-related events involved in clearance restorative mechanisms such as cough and swallow exhibit lower complexity suggesting that a synchronized homogeneous group of neurons in the central respiratory network are active during these events. Nonlinear dynamic analysis was .