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Báo cáo y học: "Primary malignant melanoma of the oesophagus: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Primary malignant melanoma of the oesophagus: a case report. | Journal of Medical Case Reports BioMed Central Case report Open Access Primary malignant melanoma of the oesophagus a case report Justin Kelly 1 Mary Leader2 and Patrick Broe1 Address Department of General Surgery Beaumont Hospital Dublin 9 Ireland and 2Department of Pathology Beaumont Hospital Dublin 9 Ireland Email Justin Kelly - jukelly@rcsi.ie Mary Leader - mary.leader@beaumont.ie Patrick Broe - patrick.broe@beaumont.ie Corresponding author Published 14 July 2007 Received 22 February 2007 Journal of Medical Case Reports 2007 1 50 doi 10.1186 1752-1947-1-50 Accepted I4 July 2007 This article is available from http www.jmedicalcasereports.eom content 1 1 50 2007 Kelly et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Primary malignant melanoma of the oesophagus is a rare neoplasm comprising less than 0.2 of all primary oesophageal neoplasms. There are fewer than 250 reported cases in worldwide literature. Several reports suggest that it has a mean survival rate of 2.2 at 5 years and a median survival rate of 10 months. A 48 year old male presented to our surgical service complaining of a three month history of progressively worsening dysphagia with associated regurgitation and unintentional weight loss of 14 kg. There was no prior history of cutaneous or ocular melanoma. He was treated with a combination of subtotal oesophageal resection and immunomodulatory therapy. We present herein a case of primary malignant melanoma of the oesophagus including the associated clinical pathological and radiological findings. Case presentation A previously healthy 48 year old male presented to our surgical out-patient service complaining of a 3 month history of progressively worsening dysphagia for solids with associated .