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Báo cáo y học: "Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy a case report Andrew W Gottschalk and John W Bachman Address Mayo Clinic Department of Family Medicine 1st Street SW Rochester MN 55905 USA Email Andrew W Gottschalk - gottschalk.andrew@mayo.edu John W Bachman - bachman.john@mayo.edu Corresponding author Published 6 January 2009 Received 14 August 2008 Journal of Medical Case Reports 2009 3 1 doi 10.1186 1752-1947-3-1 Accepted 6 January 2009 This article is available from http www.jmedicalcasereports.cOm content 3 l l 2009 Gottschalk and Bachman licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Risk of tendon rupture especially of the Achilles tendon is one of the many potential side-effects of fluoroquinolone therapy. Achilles tendon rupture may be painful debilitating or as seen in our patient devastating. While fluoroquinolone-induced tendon rupture typically accompanies other comorbidities for example renal impairment or concurrent steroid therapy our case represents a medical first in that there were no such comorbidities and no steroid therapy. Furthermore our case is remarkable in that tendon rupture was bilateral complete and resulted in a devastating outcome. Case presentation A healthy 91-year-old Caucasian man was placed on fluoroquinolone levofloxacin therapy for a presumed bacterial pneumonitis. Subsequently he developed bilateral heel pain edema and ecchymoses leading to a diagnosis of bilateral complete Achilles tendon rupture. This drug s side-effect was directly responsible for his subsequent physical and psychologic decline and unfortunate death. Conclusion .