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Báo cáo y học: " Effect of betaine supplementation on plasma nitrate/nitrite in exercise-trained men"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Effect of betaine supplementation on plasma nitrate/nitrite in exercise-trained men | Bloomer et al. Journal of the International Society of Sports Nutrition 2011 8 5 http www.jissn.eom content 8 1 5 jissn journal of the international lociety of rporti nutrition RESEARCH ARTICLE Open Access Effect of betaine supplementation on plasma nitrate nitrite in exercise-trained men Richard J Bloomer Tyler M Farney John F Trepanowski Cameron G McCarthy Robert E Canale Abstract Background Betaine beetroot juice and supplemental nitrate have recently been reported to improve certain aspects of exercise performance which may be mechanistically linked to increased nitric oxide. The purpose of the present study was to investigate the effect of betaine supplementation on plasma nitrate nitrite a surrogate marker or nitric oxide in exercise-trained men. Methods We used three different study designs acute intake of betaine at 1.25 and 5.00 grams chronic intake of betaine at 2.5 grams per day for 14 days and chronic 6 grams of betaine per day for 7 days followed by acute intake 6 grams all involving exercise-trained men to investigate the effects of orally ingested betaine on plasma nitrate nitrite. Blood samples were collected before and at 30 60 90 and 120 min after ingestion of 1.25 and 5.00 grams of betaine Study 1 before and after 14 days of betaine supplementation at a dosage of 2.5 grams Study 2 and before and after 7 days of betaine supplementation at a dosage of 6 grams followed by acute ingestion of 6 grams and blood measures at 30 and 60 min post ingestion Study 3 . Results In Study 1 nitrate nitrite was relatively unaffected and no statistically significant interaction p 0.99 dosage p 0.69 or time p 0.91 effects were noted. Similar findings were noted in Study 2 with no statistically significant interaction p 0.57 condition p 0.98 or pre post intervention p 0.17 effects noted for nitrate nitrite. In Study 3 no statistically significant changes were noted in nitrate nitrite between collection times p 0.97 . Conclusion Our data indicate that acute or chronic