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Báo cáo sinh học: " Varicella zoster virus acute retinal necrosis following eye contusion: case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Varicella zoster virus acute retinal necrosis following eye contusion: case report | Virology Journal BioMed Central Case Report Open Access Varicella zoster virus acute retinal necrosis following eye contusion case report Petra Svozílková Eva Ríhová Pavel Diblík Pavel Kuthan Zdenek Kovarík and Bohdana Kalvodová Address Department of Ophthalmology 1st Faculty of Medicine Charles University Prague Czech Republic Email Petra Svozílková - psvoz@lf1.cuni.cz Eva Ríhová - evarihova@hotmail.com Pavel Diblík - pavel.diblik@email.cz Pavel Kuthan - pavel_kuth@yahoo.com Zdenek Kovarík - b.kovarikova@iol.cz Bohdana Kalvodová - kalvodova.bohdana@vfn.cz Corresponding author Published 31 August 2005 Received 19 June 2005 Accepted 31 August 2005 Virology Journal 2005 2 77 doi 10.1186 1743-422X-2-77 This article is available from http www.virologyj.cOm content 2 1 77 2005 Svozílková et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Acute retinal necrosis is a sight-threatening disease caused by the group of herpesviruses. The aim of this paper is to report a case of acute retinal necrosis following ocular trauma in a patient initially treated with vaso-active drugs and corticosteroids for presumed ocular ischemic syndrome. Case presentation A 51-years-old otherwise healthy man who suffered from sudden visual loss in the left eye following contusion was commenced on vaso-active drugs and systemic corticosteroids for suspected ocular ischemic syndrome with extensive swelling of the optic disc and macular edema. Subsequently vision in the initially uninvolved right eye decreased. Polymerase chain reaction of vitreous samples and retinal biopsy confirmed varicella zoster virus. Despite intensive treatment with intravenous antiviral medication the patient became completely blind in both eyes. Conclusion .