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báo cáo hóa học: " Responsiveness of EORTC QLQ-C30, QLQ-CR38 and FACT-C quality of life questionnaires in patients with colorectal cancer"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Responsiveness of EORTC QLQ-C30, QLQ-CR38 and FACT-C quality of life questionnaires in patients with colorectal cancer | Uwer et al. Health and Quality of Life Outcomes 2011 9 70 http www.hqlo.eom content 9 1 70 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Responsiveness of EORTC QLQ-C30 QLQ-CR38 and FACT-C quality of life questionnaires in patients with colorectal cancer I ir tnol I 1 A or1 2 c Hrici ino Dr ll r ir l32 3 4Er3 ic 1 lillomin2 3 4 Iloilo K iinx 5 Mnưici-rhrictinQ incl x 1 Lionel uwei Ciiiistine notoilUd ridncis Guiiiemin joeiie Miny Mdiie Ciiiistine Ixdimnsky l l rioi f o l iorr ior4 6 I 2Ci1 il i2 Tmi imior-D rH7 IC3Heil Io I Ci inn rH 1 2 Dhi lir if io l lmnfr i im lof 8 DFii lir if io D I ir H9 3 f ir 1 Mdiiette Meiciei Ldetitid louiniei ndngediu Isdbeiie Leondid riiiiippe Iviontcuquet riiiiippe nducn dnu Thiei iy Conroy1 2 4 Abstract Background The dim of this study wds to compdte the responsiveness of the Eutopedn Otgdnizdtion foi Resedich dnU Tredtment EORTC qudiity of iife questionndires QLQ-C30 QLQ-CR38 dnU the Functiondi Assessment of Cdncet Therapy-coiorectdi vetsion 4 questionndire FACT-C . Method This prospective study inciuUeU 127 pdtients with coiorectdi cdncei 71 undeigoing chemotherapy dnU 56 raUidtion therapy. Responsiveness stdtistics inciudeU the SranUdfUizeU Response Medn SRM dnU the Effect Size ES . The pdtient s oveidii dssessment of his hei chdnge in stdte of hedith stdtus wds the reference criterion to evdiudte the responsiveness of the QoL questionndiies. Results 34 pdtients perceived theii hedith ds stdbie dnU 17 ds improved between the fiist dnU the fourth couises of chemotheidpy. 21 pdtients peiceiveU theii hedith ds stdbie dnU 22 ds impioveU between befoie dnU the idst week of iddiotheidpy. The iesponsiveness of the 3 questionndiies diffeied dccoiding to tiedtments. The EORTC QLQ-C30 questionndiie wds moie responsive in pdtients receiving chemotherapy pditicuidiy functiondi scdies SRM 0.55 . The QLQ-CR38 dnd the FACT-C questionndiies provided iittie ciinicdiiy ieievdnt infoimdtion duiing chemotherapy oi radiotherapy. Conclusion