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Báo cáo khoa học: Expression of Helicobacter pylori CagA domains by library-based construct screening

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Highly pathogenic strains ofHelicobacter pyloriuse a type IV secretion sys-tem to inject the CagA protein into human gastric cells. There, CagA asso-ciates with the inner side of the membrane and is tyrosine-phosphorylated at EPIYA motifs by host kinases.

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