Đang chuẩn bị liên kết để tải về tài liệu:
Lecture Genetics: From genes to genomes - Chapter 3: Extensions to Mendel's laws

Chapter 3 - Extensions to Mendel's laws. In this chapter, students will be able to: Understand incomplete dominance and its relationship to blood type, understand the idea of and give examples of pleiotropy, understand complementary gene action. | Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia CHAPTER OUTLINE Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th ed., Chapter 3 CHAPTER Basic Principles: How Traits Are Transmitted CHAPTER PART I Extensions to Mendel's laws 3.1 Extensions to Mendel for Single-Gene Inheritance 3.2 Extensions to Mendel for Multifactorial Inheritance Some phenotypic variation poses a challenge to Mendelian analysis Example: Lentils come in an array of colors and patterns Crosses of pure-breeding lines can result in progeny phenotypes that don't appear to follow Mendel's rules Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th ed., Chapter 3 Fig. 3.1 Explanations for some traits: No definitively dominant or recessive allele More than two alleles exist Multiple genes involved Gene-environment interactions Extensions to Mendel for single-gene inheritance Dominance is not always complete Incomplete dominance – e.g. snapdragon flower color Codominance – e.g. lentil coat patterns, AB blood group in humans A gene may have >2 alleles – e.g. lentil coat patterns, ABO blood groups in humans, histocompatibility in humans Pleiotropy - one gene may contribute to several characteristics Recessive lethal alleles – e.g. AY allele in mice Delayed lethality Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th ed., Chapter 3 Summary of different dominance relationships The phenotype of the heterozygote defines the dominance relationship of two alleles Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th ed., . | Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia CHAPTER OUTLINE Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th ed., Chapter 3 CHAPTER Basic Principles: How Traits Are Transmitted CHAPTER PART I Extensions to Mendel's laws 3.1 Extensions to Mendel for Single-Gene Inheritance 3.2 Extensions to Mendel for Multifactorial Inheritance Some phenotypic variation poses a challenge to Mendelian analysis Example: Lentils come in an array of colors and patterns Crosses of pure-breeding lines can result in progeny phenotypes that don't appear to follow Mendel's rules Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th .