Đang chuẩn bị liên kết để tải về tài liệu:
Results of treatment of patients with multiple organ failure supported by pre and post dilution continuous renal replacement therapy

Không đóng trình duyệt đến khi xuất hiện nút TẢI XUỐNG

Objectives: To evaluate the outcome of the patients with multiple organ failure (MOF) supported by pre-and-post-dilution continuous renal replacement therapy (CRRT) and compare some factors related to the results, progression and prognosis of the patients supported by preand-post-dilution to those by post-dilution only. | Journal of military pharmaco-medicine no2-2018 RESULTS OF TREATMENT OF PATIENTS WITH MULTIPLE ORGAN FAILURE SUPPORTED BY PRE-AND POST-DILUTION CONTINUOUS RENAL REPLACEMENT THERAPY Huynh Thi Ngoc Thuy*; Hoang Trung Vinh**; Do Quoc Huy* SUMMARY Objectives: To evaluate the outcome of the patients with multiple organ failure (MOF) supported by pre-and-post-dilution continuous renal replacement therapy (CRRT) and compare some factors related to the results, progression and prognosis of the patients supported by preand-post-dilution to those by post-dilution only. Subjects and methods: Prospective trial, compared before and after intervention in 77 patients diagnosed of MOF according to SOFA score, including 2 groups: 41 patients in group 1 (study group) (supported by pre-and-postdilution), 36 patients in group 2 (control group) (supported by post-dilution). Data were received from clinical examination, diagnostic tests during treatment. Results: Comparing with postdilution, patients in group of pre-and-post-dilution had lower serum creatinine at the end of study (1.6 ± 0.9 mg/dL versus 2.3 ± 1.5 mg/dL), higher TNF-α clearance (16.8 pg/mL versus 4.0 pg/mL), filter lifetime was longer (31.9 ± 10.8 h versus 26.7 ± 10.6 h), the percentage of patients with acute kidney injury (AKI) as well as failure of ≥ 5 were lower at the end of the study (36.6% vs 72.2% and 24.4% vs 50%). The mortality rates of the two groups were similar (70.7% and 72.2%). Conclusion: Pre-and-post-dilution has many advantages in improving kidney function, purifying cytokines and prolonging the filter lifetime. * Keywords: Multiple organ failure; Continuous renal replacement therapy; Post-dilution; Preand-post-dilution. INTRODUCTION Multiple organ failure is the disease with severely progression and makes many patients stayed at intensive care unit (ICU) for a long time. Although therapeutic progresses, the mortality rates remained the highest in ICU. So that, besides of the intensive treatment .

TÀI LIỆU LIÊN QUAN
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.