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Characteristics of bone mineral density, body composition in patients with type 2 diabetes

Objectives: To study the relationship between body composition, bone mineral density and some characteristics in patients with type 2 diabetes mellitus. Subjects and methods: A crosssectional analysis study was carried out on 151 patients with type 2 diabetes, aged 36 - 81, and examined glucose, HbA1c, insulin, and C-peptide by using the Cobas 6000 and Cobas e 601 automated systems from Roche at the Nghean General Friendship Hospital. | Journal of military pharmaco-medicine no7-2018 CHARACTERISTICS OF BONE MINERAL DENSITY, BODY COMPOSITION IN PATIENTS WITH TYPE 2 DIABETES Ngo Duc Ky*; Doan Van De**; Dang Hong Hoa** SUMMARY Objectives: To study the relationship between body composition, bone mineral density and some characteristics in patients with type 2 diabetes mellitus. Subjects and methods: A crosssectional analysis study was carried out on 151 patients with type 2 diabetes, aged 36 - 81, and examined glucose, HbA1c, insulin, and C-peptide by using the Cobas 6000 and Cobas e 601 automated systems from Roche at the Nghean General Friendship Hospital. Measurement of total body bone density by American Hologram Discovery QDR series 4500A/SL. The HOMA2IR was calculated according to the HOMA Calculator v2.2.3 software version of Oxford University (UK). Results: The avarage age of subjects was 62.12 ± 8.99 years. Average BMI was 22.96 ± 2.98 kg/m². There were no differences in age, BMI, HbA1c and HOMA2 between men and women. Bone mineral density in females (0.942 ± 0.103 g/cm²) was lower than males (1.087 ± 0.097 g/cm²). The body fat distribution, as well as total body fat of women were statistically significantly higher than men (p 0.05 76 (50.3%) 75 (49.7%) BMI (kg/m²) 23.06 ± 2.90 22.86 ± 3.07 22.96 ± 2.98 > 0.05 HbA1c (%) 7.61 ± 2.01 8.26 ± 2.08 7.93 ± 2.06 > 0.05 HOMA2-IR 7.09 ± 5.08 6.86 ± 6.27 6.97 ± 5.69 > 0.05 Age (years) Gender As we all know, type 2 diabetes mostly affects middle-aged people, although the prevalence of daytime disease is much earlier today. On the other hand, type 2 diabetes mellitus is a silent disease. Patients are often diagnosed with high blood glucose levels or have had complications of diabetes > 0.05 mellitus. The mean age of the study group was 62.12 ± 8.99 years, the youngest was 36 years old and the oldest was 81 years old. The mean age of the study was similar to that of other Asian studies [6] but was higher in some studies [4, 5]. This .