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Evaluation of the results of laparoscopic debulking surgery in the management of advanced ovarian cancer after neoadjuvant chemotherapy at Hue Central Hospital

To evaluate the feasibility and the effect of the laparoscopic debulking surgery in the treatment of advanced ovarian cancer after neoadjuvant chemotherapy. Subjects and methods: We performed a retrospective review of laparoscopic approach in patients with histologically confirmed epithelial ovarian cancer (International Federation of Gynaecology Obstetrics staged IIIC-IV) who received 3 courses of neoadjuvant chemotherapy, from January 2012 to January 2018, at Department of Obstetrics and Gynaecology, Hue Central Hospital. Results: A total of 32 patients were included. The median age was 51 years (range, 25 - 67 years), median body mass index was 24.4 kg/m2 (range, 20 - 41 kg/m2 ). All patients had good clinical response to 3 cycles of neoadjuvant chemotherapy. Most women underwent a complete debulking surgery with no residual disease (56.25%). The median operation time was 150 minutes (range, 75 - 330 minutes), the median blood loss was 85 mL (range, 55 - 220 mL). The median number of removed pelvic lymph nodes was 14 (range, 09 - 21). There was one intraoperative complication (3.13%) and two postoperative short-term complications (6.26%). The median length of hospital stay was 5 days (range, 4 - 13 days). The median follow-up was 18 months (range, 5 - 56 months). | Evaluation of the results of laparoscopic debulking surgery in the management of advanced ovarian cancer after neoadjuvant chemotherapy at Hue Central Hospital