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Spread of hepatitis E viral infection among hemodialysis patients in Pazardzhik district, Bulgaria

Hepatitis E virus is the major cause of non A enteral hepatitis. It is usually transmitted by fecal oral route, but infection is possible after bloodproducts transfusion and during birth. The medical literature data are controversial whether dialysis patients are at higher risk of infection. The aim of the study was to investigate the distribution of HEV infection (seroprevalence) in hemodialysis patients from Pazardzhik region, Bulgaria. 102 patients (58.8% men and 41.2% - women) on dialysis treatment were tested. The mean age of the men was 58.7 years, of the women – 59.7. We used epidemiological surveillance and serological testing. From the studied patients 14.7% were anti HEV IgA+IgM+IgG positive. The seroprevalence was significantly higher in male gender (p=0.039). The distribution of HEV infection in hemodialysis patients was lower in comparison to general population (14,7% vs.17%). The conclusion stresses on the need of periodic serological testing for Hepatitis E in patients on hemodialysis. | Spread of hepatitis E viral infection among hemodialysis patients in Pazardzhik district, Bulgaria