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Detection of carbapenamase resistance in non-fermenter gram negative bacilli by phenotypic methods in a tertiary care hospital

Non fermenter Gram negative bacilli were considered as contaminants or commensals of little significance1. However, recent literature review shows that these organisms are now associated with life-threatening infections such as Septicemia, Pneumonia, Urinary Tract Infection, Meningitis, Surgical Site Infection, Ventilator Associated Pneumonia, Wound Infection, Osteomyelitis etc. Carbapenemases are diverse enzymes that vary in their ability to hydrolyze Carbapenems and other beta lactams. Detection of Carbapenemase is a crucial infection control issue because they are often associated with extensive antibiotic resistance, treatment failures and infection associated mortality. | Detection of carbapenamase resistance in non-fermenter gram negative bacilli by phenotypic methods in a tertiary care hospital