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Alterations in the glycome after HDAC inhibition impact oncogenic potential in epigenetically plastic SW13 cells

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Defects in the type and degree of cellular glycosylation impact oncogenesis on multiple levels. Although the type of glycosylation is determined by protein sequence encoded by the genome, the extent and modifications of glycosylation depends on the activity of biosynthetic enzymes and recent data suggests that the glycome is also subject to epigenetic regulation. | Alterations in the glycome after HDAC inhibition impact oncogenic potential in epigenetically plastic SW13 cells

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