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Đặc điểm lâm sàng, cận lâm sàng của 81 trẻ gái dậy thì sớm trung ương tại Bệnh viện Trẻ em Hải Phòng năm 2018-2019

Nghiên cứu nhằm mô tả đặc điểm lâm sàng, cận lâm sàng của 81 trẻ gái dậy thì sớm trung ương (DTSTƯ) tại Bệnh viện Trẻ em Hải Phòng từ tháng 1 năm 2018 đến tháng 10 năm 2019. | Journal of Pediatric Research and Practice Vol. 5 No. 2 2021 10-21 Research Paper Clinical and Paraclinical Features of 81 Girls with Central Precocious Puberty at Hai Phong Children s Hospital in 2018-2019 Nguyen Dinh Le Dang Van Chuc Tran Huy Duy Hai Phong University of Medicine and Pharmacy No 72A Nguyen Binh Khiem Ngo Quyen Hai Phong Vietnam Received 15 January 2021 Revised 20 March 2021 Accepted 10 April 2021 Abstract Objective To describe clinical and paraclinical features of 81 girls with central precocious puberty at Haiphong Children s Hospital from 1 2018 to 10 2019. Methods The method was a case-series report and studied subjects included 81 girls with central precocious puberty. Subjects were enrolled in the study by a convenient method without randomized selection. Results The majority of cases 61.73 were found out at the age of 6-8 years with reason of breast growth 82.71 and first period less than 3 months. One hundred of cases showed breast growth of Tanner 2 stage or more pubic hair was found in 16.05 girls first period in 11.11 of girls and mean height increased by 2.05 0.98 cm more. Bone age was higher than that of mean real age that was 21.9 2.71 months. More than half of cases 55.56 had uterus height more than 34 mm. Most cases 87.7 were done GnRH test and test GnRH was done in 100 cases with LH lt 0 3 UI L. 100 of cases were idiopathic. Conclusions Central precocious puberty in girls often occurs at the age of 6-8 years manifesting breast growth and first period. Bone age was higher than that of real age uterus height was higher than 34 mm and this central precocious puberty was often idiopathic. Keywords Precocious puberty breast growth first period pubic hair case-series report body mass index BMI Corresponding author. E-mail address nguyendinhle86@gmail.com https doi.org 10.47973 jprp.v5i2.305 10 N.D. Le et al. Journal of Pediatric Research and Practice Vol. 5 No. 2 2021 10-20 11 Đặc điểm lâm sàng cận lâm sàng của 81 trẻ gái dậy thì sớm .