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Đặc điểm hình ảnh FDG PET/CT của u lympho không Hodgkin tế bào T

Nghiên cứu này với mục tiêu khảo sát (1) vị trí, (2) mức độ chuyển hóa của các tổn thương trong U lympho không Hodgkin tế bào T trên hình ảnh FDG PET/CT và (3) xác định tương quan giữa mức độ chuyển hóa và chỉ số Ki67. | ĐẶC ĐIỂM HÌNH ẢNH FDG PET CT CỦA U NGHIÊN CỨU KHOA HỌC LYMPHO KHÔNG HODGKIN TẾ BÀO T SCIENTIFIC RESEARCH Characteristics of T-cell non-Hodgkin Lymphomas by FDG PET CT Ngô Văn Tấn Nguyễn Xuân Cảnh SUMMARY Objective T-cell non-Hodgkin lymphomas NHL is a group of uncommon lymphomas accounting for about 12 of all cases of non-Hodgkin lymphoma. The purpose of this study is to investigate the sites and metabolic activity of lesions in T-cell NHL on FDG PET CT images and to determine the correlation between metabolic activity and Ki67. Patients and methods A retrospective study of patients with T-cell NHL who underwent FDG PET CT examination for initial disease staging from 2009 to 2019. Results A total of 62 patients 37 men and 25 women with mean age of 44.8 were included in this study. There were 30 62 patients with histopathological subtypes in which the highest frequency was peripheral T-cell lymphoma not otherwise specified and extranodal NK T-cell lymphoma nasal type with 8 cases 26.7 each. PET CT images showed the frequency of lesions in the lymph node regions in descending order of neck 67.7 axillary 41.9 mediastinum 40.3 abdomen 40.3 inguinal area 37.1 . There were 32 extranodal sites organs involved in T-cell NHL most commonly in the spleen 27.4 nasal cavity 24.2 bone marrow 22.6 nasopharynx 21 with a frequency greater than 20 . The mean SUVmax of lymph nodes in descending order was 9.9 in the abdominal lymph nodes 7.7 in the cervical lymph nodes 7.7 in the axillary lymph nodes 6.2 in the mediastinal lymph nodes 5.9 in the inguinal lymph nodes . The majority 81 of lesions in extranodal sites organs had a mean SUVmax 5. Sites organs with high frequency of lesions having the highest mean SUVmax were skeletal muscle 17.3 nasal cavity 12.3 skin subcutaneous tissue 11.7 nasopharynx 10.2 lung 6.9 pleura 6.8 bone marrow 5.3 liver 5.0 and spleen 5.0 . Analysis of the linear correlation between SUVmax of the lesion at the biopsy site and the percentage of Ki67 was .