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Pharmaceutical Substances Syntheses, Patents, Applications - Part 210

Pharmaceutical Substances Syntheses, Patents, Applications - Part 210. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Trenbolone acetate T 2091 0 2-chloro- semicorbozide 1 2 4-tHazalo- pyridine 4 3-o pyridin- 3 2H -one I 1. NqNHj or NoH 2. 2. 1- 3-chloropropyl -4- 3-chlorophenyl - piperazine Reference s . US 3 381 009 Angelini Francesco 30.4.1968 I-prior. 15.12.1965 . DE 1 645 947 Angelini Francesco appl. 13.12.1966 I-prior. 15.12.1965 3.8.1966 . Formulation s cps. 25 mg 50 mg f. c. tabl. 100 mg tabl. 50 mg 100 mg 150 mg 300 mg as hydrochloride Trade Name s D Thombran Boehringer Ing. 1977 F Pragmarel UPSA wfm I Trittico Angelini J Desyrel Pharmacia Upjohn Restin Kanebo USA Desyrel Apothecon 1982 Trenbolone acetate Trienbolone acetate ATC A14 Use anabolic RN 10161-34-9 MF C2 H24O3 MW 312.41 EINECS 233-432-5 CN 17ß -17- acetyloxy estra-4 9 l l-trien-3-one trenbolone RN 10161-33-8 MF CĨ8H22O2 MW 270.37 17 J-benzoyloxy-3-chloro-5-oxo- 4 5-seco-2 9 1 o -estradiene anhydride I 2092 T Trenbolone hexahydrobenzyl carbonate Reference s FR-M 1 958 Roussel-Uclaf appl. 13.7.1962 . GB 1 035 683 Roussel-Uclaf valid from 19.4.1963 F-prior. 20.4.1962 . Velluz L. et al. C. R. Hebd. Seances Acad. Sci. COREAF 257 569 1963 . starting material Velluz L. et al. C. R. Hebd. Seances Acad. Sci. COREAF 250 1084 1960 . alternative syntheses Heker M. et al. Steroids STEDAM 10 211 1967 . US 3 453 267 Roussel-Uclaf 1.7.1969 F-prior. 31.12.1964 25.2.1965 24.3.1965 14.6.1965 3.9.1965 17.9.1965 . use for treatment of varicose wounds DOS 2 119 096 Roussel-Uclaf appl. 20.4.1971 . Formulation s pellet 300 mg Trade Name s F Finaject Distrivet wfm Finaplix Distrivet wfm Parabolan Negma wfm Trenbolone hexahydrobenzyl carbonate atc a 14 Use anabolic RN 23454-33-3 MF C26H34O4 MW 410.55 EINECS 245-669-1 CN 17 P -17- cyclohexy lmethoxy carbonyl oxy estra-4 9 1 l-trien-3-one trenbolone cyclohexylmethyl chloroformate Trengestone T 2093 Reference s FR-M 5 979 Roussel-Uclaf appl. 17.11.1966 . Formulation s amp. 50 mg Trade Name s F Hexabolan Phartec wfm Parabolan Negma wfm Trengestone ATC G03 Use progestogen RN 5192-84-7 MF .