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Báo cáo khoa học: "The effect of intraoperative specimen inking on lumpectomy re-excision rates"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The effect of intraoperative specimen inking on lumpectomy re-excision rates | Singh et al. World Journal of Surgical Oncology 2010 8 4 http www.wjso.eom content 8 1 4 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access The effect of intraoperative specimen inking on lumpectomy re-excision rates Mansher Singh1 2 Gayatri Singh2 Kevin T Hogan1 Kristen A Atkins3 Anneke T Schroen1 Abstract Background Lumpectomy re-excision to obtain negative margins is common. We compare the effect of two specimen orientation approaches on lumpectomy re-excision rates. Methods All women undergoing lumpectomy for breast cancer by a single surgeon between 03 2007 - 02 2009 were included. Lumpectomies underwent standard inking SI after surgery by a pathologist from 03 2007-02 2008 while intraoperative inking II with direct surgeon input was done from 03 2008-02 2009. Rates of margin positivity and re-excision were compared between these methods. Results 65 patients were evaluated reflecting SI in 39 and II in 26 cases. Margin positivity rates of 46 SI vs. 23 II p 0.06 and re-excision rates of 38 SI vs. 19 II were observed. Residual disease at re-excision was found in 27 SI vs. 67 II of cases. Conclusions Intraoperative inking in this practice offered a simple way to reduce re-excision rates after lumpectomy and affect an improvement in quality of patient care. Background Achieving negative margins remains one of the most important determinants for local recurrence following breast conserving therapy 1 . Re-excision rates after lumpectomy for the treatment of breast cancer to achieve negative margins have been reported between 20-60 2-5 . Re-excision lumpectomy may lead to diminished cosmetic results delays in adjuvant therapy and additional anxiety and expense. In order to minimize the tissue volume removed at re-excision directed re-excision can be performed with accurate specimen orientation 6 . Directed re-excision of positive margins typically relies on the use of up to six multi-colored inks and reporting of separate margin status or widths. Traditionally .