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Báo cáo khoa học: "Primary appendiceal mucinous adenocarcinoma alongside with situs inversus totalis: a unique clinical case"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Primary appendiceal mucinous adenocarcinoma alongside with situs inversus totalis: a unique clinical case | Petrou et al. World Journal of Surgical Oncology 2010 8 49 http www.wjso.eom content 8 1 49 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Primary appendiceal mucinous adenocarcinoma alongside with situs inversus totalis a unique clinical case Athanasios Petrou 1 Alexandros Papalambros 1 Nikolaos Katsoulas1 Konstantinos Bramis1 Konstantinos Evangelou2 and Evaggelos Felekouras1 Abstract Introduction Mucinous adenocarcinoma is a rare neoplasm of the gastrointestinal tract and one of the three major histological subtypes of the primary appendiceal adenocarcinoma. The most common type of presentation is that of acute appendicitis and the diagnosis is usually occurred after appendectomy. The accurate preoperative diagnosis and management of the above condition represents a real challenge when uncommon anatomic anomalies such intestinal malrotation and situs inversus take place. Situs inversus totalis with an incidence of 0.01 is an uncommon condition caused by a single autosomal recessive gene of incomplete penetration in which the major visceral organs are mirrored from their normal positions. Case presentation We present an unusual case of a 59 years old previously healthy man presented with a left lower quadrant abdominal pain accompanied with low fever leukocytosis anorexia and constipation. A chest radiograph demonstrated dextrocardia with a right side positioned stomach bubble. Both preoperative US and CT scan of the abdomen and pelvis declared situs inversus with a characteristic thickening in its wall appendix situated in the left lower quadrant of the abdomen. These findings reached to the diagnosis of acute appendicitis with situs inversus and a standard appendicectomy was performed. Pathologic evaluation established primary mucinous adenocarcinoma of the appendix and three months afterwards the patient underwent a subsequent extended left hemicolectomy. Conclusion In conclusion the occurrence of primary appendiceal mucinous adenocarcinoma along .