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Báo cáo khoa học: " Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " " Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007. | Radiation Oncology BioMed Central Research Intraoperative radiotherapy IORT combined with external beam radiotherapy EBRT for soft-tissue sarcomas - a retrospective evaluation of the Homburg experience in the years 1995-2007 Marcus Niewald Jochen Fleckenstein Norbert Licht Caroline Bleuzen and Christian Ruebe Open Access Address Dept. of Radiooncology Saarland University Hospital Kirrberger Str.1 66424 Homburg Saar Germany Email Marcus Niewald - ramnie@uniklinikum-saarland.de Jochen Fleckenstein - rajfle@uniklinikum-saarland.de Norbert Licht - ranlic@uniklinikum-saarland.de Caroline Bleuzen - caro-b76@gmx.de Christian Ruebe - ruebe@uniklinikum-saarland.de Corresponding author Published 26 August 2009 Received 22 May 2009 Radiation Oncology 2009 4 32 doi 10.1186 174 -717X-4-32 Accepted 26 August 2009 This article is available from http www.ro-journal.cOm content 4 1 32 2009 Niewald et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Purpose To retrospectively evaluate the results after a regimen of surgery IORT intraoperative radiotherapy and EBRT external beam radiotherapy for soft-tissue sarcomas Methods 38 consecutive patients underwent IORT for soft-tissue sarcoma 29 were treated for primary tumours 9 for recurrences. There were 14 cases with liposarcomas 8 with leiomyosarcomas 7 with malignant fibrous histiocytomas. 27 38 tumours were located in the extremities the remaining ones in the retroperitoneum or the chest. Radical resection was attempted in all patients a R0-resection was achieved in 15 38 patients R1 in 12 38 pats and R2 in 4 38 pats. IORT was performed using a J-125 source and a HDR high dose rate afterloading .