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Báo cáo y học: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease. | Respiratory Research BioMed Central Open Access Review Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease Joanna L Richens 1 Richard A Urbanowicz 2 Elizabeth AM Lunt1 Rebecca Metcalf1 Jonathan Corne3 Lucy Fairclough2 and Paul O Shea1 Address 1Cell Biophysics Group School of Biology The University of Nottingham NG7 2RD UK 2COPD Research Group Institute of Infection Immunity and Inflammation The University of Nottingham NG7 2UH UK and 3Department of Respiratory Medicine Nottingham University Hospitals Nottingham UK Email Joanna L Richens - joanna.richens@nottingham.ac.uk Richard A Urbanowicz - rich.urbanowicz@nottingham.ac.uk Elizabeth AM Lunt - elizabeth.lunt@nottingham.ac.uk Rebecca Metcalf - plxrlm@nottingham.ac.uk Jonathan Corne - jonathan.corne@nuh.nhs.uk Lucy Fairclough - lucy.fairclough@nottingham.ac.uk Paul O Shea - paul.oshea@nottingham.ac.uk Corresponding author fEqual contributors Published 22 April 2009 Received 11 February 2009 Respiratory Research 2009 10 29 doi 10.1186 1465-9921-10-29 Accepted 22 April 2009 This article is available from http respiratory-research.com content 10 1 29 2009 Richens et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Chronic obstructive pulmonary disease COPD is a treatable and preventable disease state characterised by progressive airflow limitation that is not fully reversible. Although COPD is primarily a disease of the lungs there is now an appreciation that many of the manifestations of disease are outside the lung leading to the notion that COPD is a systemic disease. Currently diagnosis of COPD relies on largely descriptive measures to enable classification such as symptoms .