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Báo cáo y học: " Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD. | Respiratory Research BioMed Central Research Open Access Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD Paula Rytila1 Tiina Rehn2 Helen Ilumets2 Annamari Rouhos2 Anssi Sovijarvi3 Marjukka Myllarniemi2 and Vuokko L Kinnula 4 Address Division of Allergology Helsinki University Central Hospital Helsinki Finland 2Pulmonary Medicine Helsinki University Central Hospital Helsinki Finland 3Clinical Physiology Helsinki University Central Hospital Helsinki Finland and 4Department of Medicine University of Helsinki Helsinki Finland Email Paula Rytila - paula.rytila@hus.fi Tiina Rehn - tiina.rehn@hus.fi Helen Ilumets - helen.ilumets@hus.fi Annamari Rouhos - annamari.rouhos@hus.fi Anssi Sovijarvi - anssi.sovijarvi@hus.fi Marjukka Myllarniemi - marjukka.myllarniemi@hus.fi Vuokko L Kinnula - vuokko.kinnula@helsinki.fi Corresponding author Published 28 April 2006 Received 03 November 2005 Respiratory Research 2006 7 69 doi 10.1186 1465-9921 -7-69 Accepted 28 April 2006 This article is available from http respiratory-research.eom content 7 1 69 2006 Rytila et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Chronic obstructive pulmonary disease COPD is associated with increased oxidative and nitrosative stress. The aim of our study was to assess the importance of these factors in the airways of healthy smokers and symptomatic smokers without airway obstruction i.e. individuals with GOLD stage 0 COPD. Methods Exhaled NO FENO and induced sputum samples were collected from 22 current smokers 13 healthy smokers without any respiratory symptoms and 9 with symptoms i.e. stage 0 COPD and 22 healthy age-matched non-smokers II never smokers and II ex-smokers . Sputum cell differential .