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Báo cáo y học: "The use of cephalad cannulae to monitor jugular venous oxygen content during extracorporeal membrane oxygenation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The use of cephalad cannulae to monitor jugular venous oxygen content during extracorporeal membrane oxygenation. | Pettignano et al. Critical Care 1997 1 95 http ccforum.com c CRITICAL CARE RESEARCH Open Access The use of cephalad cannulae to monitor jugular venous oxygen content during extracorporeal membrane oxygenation Robert Pettignano1 Michele Labuz2 Theresa W Gauthier3 Jeryl Huckaby2 Reese H Clark3 Abstract Background When used during extracorporeal membrane oxygenation ECMO jugular venous bulb catheters known as cephalad cannulae increase venous drainage augment circuit flow and decompress cerebral venous pressure. Optimized cerebral oxygen delivery during ECMO may contribute to a reduction in neurological morbidity. This study describes the use of cephalad cannulae and identifies rudimentary data for jugular venous oxygen saturation JVO2 and arterial to jugular venous oxygen saturation difference AVDO2 in this patient population. Results Patients on venoarterial VA ECMO displayed higher JVO2 P 0.01 and lower AVDO2 P 0.01 than patients on venovenous VV ECMO P 0.01 . During VV ECMO JVO2 was higher and AVDO2 lower when systemic pH was 7.35 rather than 7.4 P 0.01 . During VA ECMO similar differences in AVDO2 but not in JVO2 were observed at different pH levels P 0.01 . Conclusions Jugular venous saturation and AVDO2 were influenced by systemic pH ECMO type and patient age. These data provide the foundation for normative values of JVO2 and AVDO2 in neonates and children treated with ECMO. extracorporeal membrane oxygenation venovenous ECMO venoarterial ECMO cephalad cannulae jugular venous oxygen content Introduction Extracorporeal membrane oxygenation ECMO is used to treat newborn infants and children experiencing lifethreatening cardiorespiratory failure unresponsive to conventional medical therapy 1 2 . Infants meeting the required criteria are estimated to have 80 mortality if they do not receive ECMO compared to approximately 80 survival for those who do receive the treatment 3 . This survival is not without significant cost and morbidity 2 . Substantial investigative .