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Báo cáo y học: "Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in Danish horses"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in Danish horses. | Hansen et al. Acta Veterinaria Scandinavica 2010 52 3 http www.actavetscand.eom content 52 1 3 AVS ACTAVETERINARIA SCANDINAVICA RESEARCH Open Access Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in Danish horses Marie GB Hansen1 2 Mette Christoffersen2 Line R Thuesen1 Morten R Petersen2 Anders M Bojesen1 Abstract Background Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum are able to infect horses. However the extend to which Danish horses are infected and seroconvert due to these two bacteria is unknown. The aim of the present study was to evaluate the seroprevalence of B. burgdorferi sensu lato and A. phagocytophilum in Danish horses. Methods A total of 390 blood samples collected from all major regions of Denmark and with a geographical distribution corresponding to the density of the Danish horse population were analyzed. All samples were examined for the presence of antibodies against B. burgdorferi sensu lato and A. phagocytophilum by the use of the SNAP 4DX ELISA test. Results Overall 29.0 of the horses were seropositive for B. burgdorferi sensu lato whereas 22.3 were seropositive for A. phagocytophilum. Conclusions Antibodies against B burgdorferi sensu lato and A. phagocytophilum are commonly found among Danish horses thus showing that Danish horses are frequently infected by these organisms. Background The vector-borne bacteria Borrelia burgdorferi sensu lato B. burgdorferi s. l. and Anaplasma phagocytophi-lum infect horses in those parts of the world where Ixodes spp. are present. It has been estimated that up to 30-40 of horses in an endemic area are seropositive for B. burgdorferi s. l. 1 . Most of these horses will remain asymptomatic while 5-10 of them are likely of developing clinical signs 1-4 . Similar a previous study on A. phagocytophilum have indicated that up to 50 of seropositive horses in endemic areas undergo a sub-clinical infection 5 . It is assumed that clinical equine granulocytic .